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Taka
Joined: 06 Nov 2007
Posts: 125
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 Posted: Sat Feb 23, 2008 7:53 am Post subject: Excitotoxins - MSG |
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Taka
Joined: 06 Nov 2007
Posts: 125
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| Posted: Sat Feb 23, 2008 8:02 am Post subject: Re: Excitotoxins - MSG |
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You know what VitB6 is good for - synthesis of EFAs such as the Mead
acid in the body. The following paper suggests that Chinese
restaurants can make you truly EFAD ...
Taka
The biochemistry of vitamin B6 is basic to the cause of the Chinese
restaurant syndrome.
Folkers K, Shizukuishi S, Willis R, Scudder SL, Takemura K,
Longenecker JB.
The concept of this basic research was that monosodium L-glutamate
could reveal a deficiency of vitamin B6 by the neurological reactions
known as the Chinese Restaurant Syndrome. An other amino acid,
tryptophan, administered to subjects, is known to reveal a deficiency
of vitamin B6 by the excretory xanthurenic acid, etc. The presence and
degree of a deficiency of vitamin B6 in 155 students on no
supplemental B6 was determined by the differential assay of aspartate
transaminase of erythrocytes which also allows each subject to be a
control. Twenty-seven of 155 students had extraordinarily low basal
specific activities of the transaminase, less than 0.26 mumol pyruvate/
(h X 10( erythrocytes). These 27 were challenged with glutamate and
a placebo. Twelve of 27 revealed the Chinese Restaurant Syndrome, and
15 did not. By double blind trials, the 12 "responders" were treated
with pyridoxine and a placebo for twelve weeks, and then were
rechallenged with glutamate and a placebo. Decoding showed 3 of 12
received placebo to pyridoxine and then revealed the symptoms of the
syndrome again to glutamate; 9 of 12 received pyridoxine and then 8 of
9 failed to respond to glutamate. These results show, p less than
0.01, that the symptoms of the Chinese Restaurant Syndrome to oral
glutamate fail to reoccur after treatment which pyridoxine, and that
the biochemistry of vitamin B6 is basic to the cause of the Chinese
Restaurant Syndrome.
PMID: 6724532
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